With a lean on Chimamanda Ngozi Adichie’s Americanah (2013), the article examines the entwined historical and material conditions of the contemporary world that have resulted to structural and topical challenges in African literature. This interrogation finds voice in the fact that unlike the almost exclusively nationalist and anti-colonial perspectives of earlier African literary texts, Adichie (2013) instead x-rays a distinctly global perspective; a worldwide viewpoint which entwines with the local and generates novel thematic perspectives in literature. The article thus x-rays both contemporary ways of composing, ingesting and distributing literature, and how these novelties process and strengthen global mindfulness. Though the study celebrates the asymmetrical voices of the postcolonial and the global giving-in to each other, it as well chastises the conflicts generated in contemporary citizenry by the multiple voices that simultaneously inform the dual. Despite the article’s posthuman echoes, it turns to postmodernism for analysis though principally, through Kristeva’s concept of intertextuality, Baudrillard’s discourses on time and space, and the destruction of the real. The paper is guided by the premise that twenty first century African literature negotiates the complexities of a globalized world and redefines the scope and relevance of the literature.